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Perks like armsman for example are useless in unarmed combat. One-Handed tree perks only affect equipped one handed weapons. The only perks that enhance unarmed combat are Fists of Steel (heavy armor tree), Poison Talons (vampire lord tree) and Necromage (restoration tree). Great/Critical Charge is a great way to start such a fight, and you can even set up for it from Stealth with Silent Roll. Just Bashing can turn a duel into a one-sided beating even with a Battleaxe.
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